Propecia pills use to treat male hair loss problem within a few months. It is worldwide famous medicine due to their effective working ability to protect hair. Propecia generic name is Finasteride and available in a dispensary through a generic name. Few side effects which is common for all age group who used Propecia (Finasteride) high dosage:
- Impotence (inability to take effective action),
- Loss of interest in sexual intercourse (physical and mental stress),
- Trouble having an orgasm (inability to achieve sexual climax),
- Abnormal premature ejaculation causes (semen enters the bladder instead of emerging through the penis),
- Swelling in your hands or feet (painful),
- Swelling or tenderness in your breasts,
- Dizziness (dizziness include migraine, medications, and alcohol),
- Weakness (don’t able to do work),
- Headache (pain in head),
- Runny nose/skin rash.
Allergic reaction: face swelling, lips swelling, tongue and throat dryness.
What Is Finasteride?
Basically, Finasteride is a prescription medication. This drug comes as an oral medicine. However, this Finasteride medicine is available under the brand-name drugs Propecia and Proscar. Although this drug is also available as a generic drug.
In addition, generic drugs normally cost much less than the brand-name version. However, in some cases, these medicine may not available for you in every strength or form as the brand-name drug.
Why Finasteride Is Used?
Well, the situation in that finasteride medicine is utilized to treat the problem is basically depends on the kind of drug that is used. However, the Proscar is utilized to treat the symptoms of enlarged prostate known as benign prostate hyperplasia. Although this medicine can be applied as part of compound therapy.
Basically, it means you require to use it with some other drugs. It also can be taken with doxazosin to reduce the risk of progression of symptoms of the enlarged prostate. Basically, the Propecia drug is used to treat pattern hair loss in males. Finasteride is not prescribed for treatment in women or children.
How Finasteride Works?
Certainly, Finasteride is worked by reducing the quantity of the hormone named dihydrotestosterone (DHT) in your body. However, DHT commonly affects your prostate to become larger. Therefore the reduction in DHT can help you to prevent your prostate from getting larger.
In addition, this also leads to enhanced growth in hair and reduced loss of the hair on your head. Besides that, the hair growth in other parts of the body is not affected.
Male’s Breast cancer side effects can be seen by this disease
- Lumps in the breast,
- Tenderness and pain near the breast,
- Discharge from nipple,
- Changes in breast size.
Few more side effects, which is common are mention below:
- Lack of sex interest,
- The feeling of lost,
- Orgasm related issues,
- Abnormal ejaculation and behavior.
Propecia side effects due to long term treatment
In 1 of 10 people, suffering from hair loss, and their stress for hair can be seen in words also(during the talk). According to a new study investigation, sexual drugs side effect can lead to hair fall.
According to lab tests Finasteride works by hunk the production of dihydrotestosterone (DHT). A vigorous form of testosterone, which increases male baldness. This medicine is approved by the FDA to prevent hair loss and widely used all over the world for treatment.
Very few medicines are available in the market, which doesn’t have side effect but if you are talking about Propecia then you feel sad due to the list of side effects. Few major side effects are libido and erectile dysfunction (reported during the clinical trials). According to FDA update, sexual side effects might endure at least 3 months after stopping the treatment of this medicine.
Some fascinating headlines are circulating the internet to suggest that taking Propecia can cause irreversible erectile dysfunction or decrease your libido for good. FDA issued a warning in 2012 that Propecia (Finasteride) increases the risk of experiencing sexual side effects including libido, ejaculation, and orgasm disorders, which do not tell the full story in the headlines.
“According to a new study, by Steven Belkin (assistant professor of Northwestern University) men’s towel on libido. Earlier, Finasteride and Mideastern cause sexual problems that continue for more than 90 days after stopping the drugs.”
Take a close look of Propecia side effects due to long term use:
- Loss of interest in sex,
- Orgasm problem,
- Not a feeling of any excitements,
- Nipple discharge (Man’s chest),
- Changes in male breast size,
- Abnormal ejaculation (abnormal ejaculation),
- The problem of having an orgasm (the climax of sexual excitement).
Some Major Side Effects of Propecia
Well, some of the most commonly described opposing effects of Propecia (finasteride) mainly influence the sexual health of men. However, there are not any obvious or causal links within the use of any sexual side effects, and hair-growth drugs have been discovered.
Although finasteride suppresses the dihydrotestosterone or DHT hormone, which performs a significant role in the sexual development and sexuality of a person, making the bond extremely plausible. However, reducing the levels of DHT in the human body can improve hair loss problems.
But this problem may appear because the sex hormone is more essential for supporting the fundamental integrity of signaling pathways, connective tissue, smooth muscle, and nerves in the penis. Although in some clinical trials, one or more percent of the men who used Propecia experienced erectile dysfunction.
Besides that, they also feel ejaculatory disorder and reduced libido. Also, some additional studies determined these side effects continued in men even after they discontinued taking the medication.
Although the use of Propecia additionally has been connected with various ejaculatory dysfunctions. Basically, ejaculatory disorders range from premature or rapid ejaculation to delayed ejaculation also to a full incapacity to ejaculate. Also, a review of random finasteride trials noticed more men who used the medication reported ejaculation disorder than those men who got a placebo.
However, the research study in BMC Urology observed at five double-blind, placebo-controlled trials lasting 12 months. The authors estimated the relative chance for ejaculation disorder was 3.6 percent for such men using finasteride. Although the prospect study also observed notable progress in ejaculatory disorders among finasteride users.
The frequency was 7.7 percent for those men who used the medication compared to 1.7 percent amongst men who got a placebo. Meanwhile, the review in 2003 the International Journal of Impotence Research discovered between 2.1 and 7.7 percent of men using the medication in studies informed ejaculatory disorders.
Ejaculatory disorders connected with Propecia treatment involve:
- Reduction in semen volume
- Failure of Ejaculation
- Retrograde ejaculation (when semen moves reversed into the bladder rather than going forward or out of the penis)
Erectile dysfunction is also known as ED in short. This problem arises when a man has difficulty while getting an erection or keeping it. However, this problem becomes more obvious when men get maturer. Although it is not viewed as a fundamental part of aging. Therefore it is also a side effect that frequently arises in studies of finasteride.
In addition, it includes randomized, double-blind, or placebo-controlled trials. That is also called the gold standard for medical studies. However, the prospect study was also one of those trials. Basically, a whole of 472 normal men aged between 45 to 80 got either a placebo or finasteride for two years.
However, according to the authors of the study, the ratio of sexual dysfunction problems was much higher in those men who received finasteride in comparison to those men who received the placebo. Impotence happened in 15.8 percent of users of finasteride while 6.3 percent users of placebo reported the issue.
The authors of the research published the results in the Canadian Medical Association Journal issue of November 1996 year. In addition, a much more extended observational cohort study was published in 1996 within the British Journal of Urology.
That journal was used in the monitoring of prescription-event to collect more information on 14,772 patients. However, Erectile dysfunction was the most commonly reported side effect of finasteride in those days. Also, it was the most obvious cause of discontinuing the medication.
Loss of Libido
Although in some other major side effects which described during the use of Propecia is basically a decreased interest in sex. In fact, the loss of libido was the most frequent sexual side effect that was reported in a study about users of finasteride, which was published in the Journal of Sexual Medicine.
Although the researchers of the George Washington University School of Medicine examined 71 patients. All those patients have undergone some sexual side effects after taking the finasteride drug. However, the researchers discovered that 94 percent of men underwent a drop in their libido.
Though, the percentage at which reduced libido occurred that differs from study to study. After that, the American Urological Association known as Benign Prostatic Hyperplasia (BPH) guidelines committee conducted a meta-analysis. According to that analysis, the rate of reduced libido was five percent in those men using finasteride.
But it was only three percent in those men who were using a placebo. However, the review in the International Journal of Impotence Research discovered the loss of libido was recorded in 3.1 to 5.4 percent of finasteride users. After that, a review in The Journal of Clinical and Aesthetic Dermatology discovered 2.36 to 10 percent of persons on the medicine reported the side effect in comparison to 0.5 percent to 1.7 percent to placebo users.
Although these important and undesirable difficulties in connection to a sexual function provide a well-documented negative influence on the quality of life, it is written from the authors of the review. Thus, optimal medication for men with BPH needs the use of agents that explain efficiency and safety with lesser sexual side effects.
Persistent Erectile Dysfunction
Well, a Northwestern Medicine study discovered that a few men who used finasteride experienced persistent erectile dysfunction in which they were not fit to have regular erections for months or years after quitting the medication. Therefore out of 11,909 persons who used dutasteride or finasteride,
According to the study, 1.4 percent acquired persistent erectile dysfunction that stayed for an aggregate of about 1,350 days after stopping the medication. Young men who had more than 205 days of exposure to the medication had nearly five times greater risk of persistent erectile dysfunction than men with shorter exposure.
Propecia side effects forum (People’s Experience)
A shameful thing in a teenager, losing his/her hair. All over the world people are suffering from this, few of them are taking medicine or doing natural treatment. Propecia is a drug which is used for preventing hair fall.
The result of this medicine is good for hair. But the side effect of this medicine can cause a big problem for you.
World Health Organization Review
According to WHO (World Health Organization), 59 man had killed themselves due to the side effects of Finasteride. The drug doesn’t kill anyone directly but the physical/mental condition makes it difficult for people to live a normal life.
- In 2012, when I was 20 years old, I took Finasteride for 21 days. On 22 day I was traveling in public transport, started feeling uneasy and a little skeptical.
The symptoms which were felt by me at that time are dull(weakness) & headache. I also feel anxious, depressive and my sleep was nonexistent.
- I am Robert, an old user of Finasteride in the form of Propecia tablets. The result of this medicine makes my smile special by providing me a gift of my hair. But I realize my penis turned completely into a different body part (can’t able to enlarge my penis) and it was not the same.
Touching it was like touching my elbow or some other less sensitive body part, and if it did not happen at all, then there would be no real erections again.
- I am 28 years, W. Jack (Liverpool, Allerton, UK) had suffered a lot after taking this medicine. It was true, that I got a benefit from this medicine(to prevent hair loss).
After taking this medicine for a long time, my sexual organs are not operating well, I also realize, have lost fluency in my speech and thought during a talk, memory problem.
Propecia side effects percentages
- On more than 11,000 men, who took the drug had not suffered from sexual dysfunction, but after stopping the medicine 1.4% person suffered from sexual issue.
- 15,634 men, who had taken Propecia drug, no prior sexual dysfunction, 699 (4.5%) develop new ED. 1.3% man in between the age 16 to 42-year-old ha of developed new low libido.
- Younger women, who had taken medicine more than 205 days, 4.9% high risk of PDE than men.
- Sexual adverse effects are the most common side effects which cause due to this medicine from 0.9 to 38 percent of people are suffering from this drawback.
- Erectile Dysfunction, decreased libido and ejaculate ratio in percentages as 3.4% to 15.8%.
- Androgenic Alopecia (AGA) is an inborn trend of hair fall where the terminal hair is converted to scale velvety hair. According to reports, 80 percent of Caucasian men and 50 percent of women in the age of 70 years exhibit different patterns of hair loss. People, however, different examples of male pattern baldness.
- In men, hair loss is usually reduced in front & vertex side of the scalp, while women reduce from the central scalp.
Precautions Regarding Finasteride
Although it is extremely essential that your health specialist monitor the progress of this drug at regular appointments. Basically, this will enable your doctor to view if the medicine is working correctly or not. Also, it allows them to decide either you should proceed to use it or stop taking it. Besides that, blood tests can also be needed to examine for unwanted impacts.
However, children and women must not take this medicine. Because if you are a pregnant woman or would like to become pregnant then you should not touch crushed or broken pills. Because Finasteride may be absorbed into the skin. After that, it can cause childbirth deficiencies in male babies. When a woman does come in touch with this medicine, the touched area must be cleaned right away with water and soap.
This medicine can generate changes to the tissue of the breast. Although you must tell your doctor if you have any pain, tenderness, lumps, or an enlargement of the breasts during the use of this medicine. However, this medicine will not stop prostate cancer but it may raise the risk of acquiring high-grade prostate cancer.
Therefore must consult with your doctor if you have concerns about such risk. However, this medicine may change the outcomes of the prostate-specific antigen (PSA) test, which may be utilized to identify prostate cancer. But make sure you tell all things to your doctors that when you are taking this medicine.
Basically, this medicine can also cause a reduction in the quantity of semen you will ejaculate during the sex with your partner. However, this will not harm the sperm count in your semen, or your capability to become father of a children.
Difficulties May Remain After Leaving Propecia
Well, on the basis of the early trials of this Propecia medication. Merck and the FDA both promised to the men that the sexual difficulties will be solved when they will discontinue taking the medication, although the later evidence would show the opposite. Therefore the preapproval trials were not particularly reliable.
Because the data was extracted from a comparatively small group of patient those who treated only for six months to one year time period. Besides that, follow-up methods were not so clear. Although some more recent studies confirm that the sexual side effects of the medication may continue even after a man quits using the medication.
In addition, in a few cases, the difficulties are unchangeable. Although some researchers at Boston University School of Medicine in 2010 published a case study of a man, aged 24 years who began to using Propecia drug in 1999. However, the man felt soreness in his testicles in just one week’s usage of the treatment. In addition, the reduction of sex drive, and the incapability to gain an erection.
Therefore the man discontinued using the medication around a month later from when he started that drug. Besides that, when some of the side effects of that drug disappeared, then also the sexual abilities and of that man never turned to normal again. During a long time period of 11 years still, that man experienced a loss of libido and some erectile dysfunction.
The researchers published their research in the Journal of Sexual Medicine. In the year 2011, George Washington University urologist Michael S. Irwig and his colleague Swapna Kolukula issued their assessment of 71 patients of finasteride drug, who reported long-term sexual side effects that continued after quitting the medicine.
The chosen group of patients involves some young men between the ages of 21 and 46 who took a survey that exposed a large number of sexual side effects that occurred after the use of Propecia. That also including problems with arousal, erectile function, orgasm, sexual desire, and orgasm satisfaction.
The men who had used the medication for an average time of 28 months. In his case, the sexual side effects also continued for an average of 40 months, even after the men discontinued using the medicine. Upon following up with the total number of 54 of such patients one year later.
Irwig found that 96 percent of the men were still experiencing the sexual dysfunctions which they reported initially. However, none of the men reported psychiatric, sexual, or medical objections before taking the finasteride drug. Although within the review of 2014 in the Korean Journal of Urology. It discovered at least four previous investigations that reported irreversible or persistent sexual side effects.
The authors stated that the studies reported a negative emotional toll and reduced quality of life for the men who were affected. Basically, the argument that the advantages of these drugs surpass the risks is slowly disintegrating in the face of new developing scientific proof from preclinical and clinical studies, written by the authors.
Besides that, the men who experienced the long-term sexual dysfunction after he using the Propecia drug have also filed a lawsuit against Merck that accuses the organization of failing to warn the users of this drug about the risk.